The gastric sleeve, also known as the vertical sleeve gastrectomy (VSG), is one of the most popular weight loss procedures in New Jersey, and the most performed weight loss surgery here at New Jersey Bariatric Center®.
At New Jersey Bariatric Center® we get a lot of questions about gastric sleeve surgery, also known as the sleeve gastrectomy, from how it helps you lose weight to the health benefits for the procedure. If you’re considering a gastric sleeve surgery, here’s 4 FAQs about the gastric sleeve:
1. Gastric Sleeve Helps You Lose Weight in 2 Ways
First, gastric sleeve surgery jumpstarts weight loss by removing a portion of the stomach and narrowing the remaining part of the stomach into a thin “sleeve-like” tube. The reduced stomach size holds less food so you feel full faster, while still allowing for the digestion of key nutrients. The second way is that the gastric sleeve procedure reduces the secretion of ghrelins in your stomach. Ghrelins are hormones responsible for making you feel hungry. Patients on average can lose about 40-70% of their excess body weight after a gastric sleeve procedure.
2. Gastric Sleeve Health Benefits Go Beyond the Numbers on the Scale
Not only does the gastric sleeve help you to lose weight, but it can also offer other health benefits and improvements for obesity-related conditions. In a study by the American Society for Metabolic and Bariatric Surgery (ASMBS), after gastric sleeve surgery:
77% of patients had resolution of Type 2 diabetes*
62% of patients had resolution of high blood pressure*
84% of patients had resolution of sleep apnea*
As with any surgery there are side effects and risks to weight loss procedures. To learn more, visit our Side Effects & Risks page.
3. Gastric Sleeve Surgery is performed Laparoscopically or Robotically-Assisted
During gastric sleeve surgery our bariatric surgeons make small incisions in the abdominal wall to remove 75-80% of the stomach. This reduces the capacity of the stomach to 3-4 ounces, resulting in patients feeling full, faster on a smaller portion of food. At New Jersey Bariatric Center® the surgery is performed either laparoscopically or is robotically-assisted, and usually lasts approximately 1-2 hours.
4. Hospital Stays After the Gastric Sleeve Procedure are Generally 1 Day
Both methods - laparoscopic or robotic-assisted - of gastric sleeve surgery involve smaller incisions through the stomach, which often leads to, for many patients, less pain and a short, 1 day hospital stay, in general. To learn more about recovery at home, post-surgery nutrition as well as returning to work and regular activity, click here.
For more questions about gastric sleeve or to schedule an appointment with our bariatric surgery weight loss specialists give us a call at 908-481-1270. To register for one of our free webinars, click here.
*Metabolic and bariatric surgery. (2018, October). In the American Society for Metabolic and Bariatric Surgery. Retrieved November 10, 2020, from https://asmbs.org/resources/metabolic-and-bariatric-surgery
Gastric Sleeve vs Gastric Bypass: Which Bariatric Surgery Is Right For You?
Key Takeaways
Gastric Sleeve vs Gastric Bypass Differences: Gastric sleeve removes a portion of the stomach, while gastric bypass creates a small stomach pouch and reroutes the digestive pathway.
Weight Loss Results: Gastric bypass patients lose 65-75% of excess body weight, while gastric sleeve patients typically lose 60-70%.
Health Benefits: Both procedures effectively treat obesity-related conditions like diabetes and sleep apnea through weight loss and hormonal changes.
Cost Considerations: Gastric sleeve costs $8,500-$18,500, while gastric bypass ranges from $15,500-$18,500, with insurance coverage options available in New Jersey.
Bariatric surgery for obesity can be a life-changing step for many people in New Jersey, and the decision between a gastric sleeve vs gastric bypass procedure can lead to a lot of questions. Choosing the right bariatric surgery becomes less overwhelming when informed, and a consultation with a fellowship-trained, board-certified NJ bariatric surgeon can help you decide between having a gastric sleeve vs gastric bypass. Before deciding whether the gastric sleeve vs gastric bypass surgery is right for you, consider thesekey factors:
How the Gastric Sleeve vs Gastric Bypass Surgery Jumpstarts Weight Loss
Bariatric Surgery, whether Gastric Sleeve or Gastric Bypass, decreases the size of your stomach, which limits the amount of food you can eat at one time. This results in leaving you feeling fuller sooner and longer. And, with both the gastric bypass or gastric sleeve procedure, you will decrease your levels of hunger hormones so you will feel less hungry. As you eat less food, your body will stop storing excess calories and start using its fat supply for energy.
The gastric sleeve (sleeve gastrectomy, VSG) surgery jump starts weight loss by removing a portion of the stomach and narrowing the remaining part to the size of a banana or a thin vertical “sleeve.” The gastric bypass aids in weight loss by creating a small stomach pouch and rerouting the standard path food takes through the digestive system so that it “bypasses” a large section of the stomach and a portion of the small intestine.
Gastric Sleeve vs Gastric Bypass: Determine Your Weight Loss Goal
All bariatric surgery procedures, including Gastric Sleeve and Gastric Bypass, will result in an initial weight loss, but the amount lost can differ depending on which procedure you choose and the changes you commit to after surgery.
Patients who choose the gastric sleeve can see a loss between 60 to 65 percent of their excess body weight. Gastric bypass can result in a bit more weight loss with 65 to 75 percent of excess body weight.
In this video, Dr. Buwen discusses weight loss with Gastric Sleeve vs. Gastric Bypass
Consider Your Medical Conditions When Evaluating Gastric Sleeve vs Gastric Bypass
The gastric bypass and gastric sleeve procedures are some of the most effective treatments for obesity-related illnesses like type 2 diabetes. The hormonal effects surgery has on the body can have a positive impact on a patient’s blood sugar. Additionally, people with sleep apnea can see improvements and/or resolution of their condition with surgery. Less weight means less of a chance for blocked airways while sleeping.
What is the cost of Gastric Sleeve vs Gastric Bypass?
When comparing bariatric surgery options, gastric sleeve procedures typically cost $8,500 to $18,500, while gastric bypass ranges from $15,500 to $18,500 for self-pay patients. This cost difference reflects gastric bypass surgery's greater complexity. Both procedures may be covered by health insurance for many people in New Jersey, making them a more affordable long-term weight loss option. While insurance typically covers most surgical costs, out-of-pocket expenses vary by your specific policy. New Jersey Bariatric Center® offers comprehensive insurance support with upfront benefit verification before your first appointment, and accepts many insurance plans except Medicaid and NJ FamilyCare. Our navigation team guides patients through insurance approvals with a strong success rate. For patients without full coverage or facing high deductibles, flexible financing through CareCredit is available.
Commit to Follow-Up Visits to Monitor Your Progress
Whether you choose the gastric sleeve or the gastric bypass surgery, you will need to routinely meet with your surgeon and nutritionist to ensure you are on the right track. Attending support groups frequently helps you stay motivated. You can connect with others who are going through a weight loss journey too. NJBC is composed of a team of weight loss experts including fellowship-trained bariatric surgeons, on-site nutritionists and psychologists. They help guide you through this weight loss journey and beyond.
For information about the procedures including benefits and risks, click here.
Frequently Asked Questions
Which is better Gastric Sleeve or Gastric Bypass?
Determining whether a gastric sleeve or gastric bypass is 'better' depends on individual patient needs and goals. Gastric bypass typically results in slightly more weight loss (65-75% of excess body weight) compared to gastric sleeve (60-70%). However, both procedures effectively treat obesity and improves, and in some cases resolves, obesity-related illnesses such as type 2 diabetes, high blood pressure and sleep apnea.
The right procedure is determined by a patient and their doctor, after a through review of medical history, and weight loss goals. Consult with a qualified bariatric surgeon to determine which procedure is right for you.
Can you eat more with Gastric Sleeve or Gastric Bypass?
Both the gastric sleeve and gastric bypass reduce the amount of food you can consume at one time. However, because the gastric bypass creates a smaller stomach pouch and reroutes the digestive tract, it may result in slightly greater restriction in food intake compared to gastric sleeve. Neither procedure allows for large meal consumption. Both procedures are designed to restrict the amount of food a person can eat at one time. And, to also decrease the hunger hormone - grehlin. Each procedure results in feeling full faster, and for longer periods of time.
What are the side effects of Gastric Sleeve vs Gastric Bypass?
Side effects occur with bariatric surgery mainly because of the amount of weight lost in such a short period of time. Both gastric sleeve and gastric bypass surgeries carry potential side effects. General side effects can include nausea, vomiting, gallstones and lactose intolerance. Side effects for gastric bypass specifically include dumping syndrome and mineral and vitamin deficiencies. Regularly taking vitamins, minerals and protein supplements can prevent deficiencies. Also, routinely see your doctor and a registered dietitian to be tested for any deficiencies. Many of these side effects are seen in people who have lost a significant amount of weight without surgery also.
New Jersey Bariatric Center moves to Telemedicine
Telemedicine now available at NJBC
In our effort to help stop the spread of COVID-19 and accommodate our patient’s needs, New Jersey Bariatric Center now offers telemedicine appointments.
Scheduling a Telemedicine Appointment
Call our office at 908-481-1270 or click here to schedule a telemedicine appointment. After scheduling, patients will receive a confirmation email from us with a link to access their appointment. Telemedicine appointments will be conducted via Doxy.me. The platform is secure, easy-to-use and allows patients to stay connected with their New Jersey Bariatric Center doctors. Telemedicine appointments are available for current and new patients.
What to Expect during a Telemedicine Appointment
During a telemedicine session, patients will speak directly with a member of the New Jersey Bariatric Center clinical staff – surgeons, physician assistant or nutritionists – based on the type of appointment they schedule. Current pre-op patients can stay on track for their future procedures, new patients can learn about weight loss surgery procedures like the gastric sleeve and gastric bypass and post-op patients can maintain their care and follow-up.
At New Jersey Bariatric Center the safety of our patients, staff and communities we serve is a priority. We hope by introducing telemedicine to our patients during the NJ Coronavirus Stay-At-Home Order we can keep everyone safe, healthy and on their weight loss journey.
For more information about scheduling a telemedicine appointment or if you have questions about an existing appointment, please call our office at 908-481-1270.
Amazon’s New GLP-1 Program: What It Covers And What Else to Consider
The difference between a transaction and a transformation matters.
Short Answer: When comparing providers, look beyond the medication. While Amazon's GLP-1 program through One Medical covers prescription access, clinical monitoring, and same-day medication delivery, ensure your choice includes dedicated nutrition counseling, support groups and muscle maintenance, as these are essential to preventing weight regain and protecting your metabolism. According to clinical trial data GLP-1 medications like Wegovy® and Zepbound® produce stronger outcomes when combined with diet and exercise.
Key Takeaways
Nutrition counseling, muscle preservation support, and hands-on side effect support, all key in successful outcomes of GLP-1s for weight loss, are not included in Amazon's program.
Muscle loss is a documented risk during GLP-1 (Wegovy® and Zepbound®) use that requires active clinical management, not just weight tracking.
Amazon’s program is built around providing patients with access to weight loss medications; this covers prescribing the medication, monitoring progress and same-day delivery.
At New Jersey Bariatric Center®, the program has a focus on long-term maintenance and expert support. Muscle preservation classes, nutrition education led by registered dietitians and hands-on side effect support directly from clinicians are included.
What to ask any program: Before starting GLP-1 weight loss programs, it's worth asking how muscle loss is monitored, what nutrition support looks like, and how common side effects like nausea are managed if they arise.
Amazon's new GLP-1 program through One Medical is one of the most talked-about developments in weight loss. For many, the idea of getting a GLP-1 prescription like Wegovy® or Zepbound® with the same ease as ordering a household essential is tempting.
While increased access to weight loss medications is a step forward for public health, it’s important for people considering GLP-1 weight loss medications to take a closer look at what’s included. When it comes to obesity care, the difference between a transaction and a transformation matters. If you are researching, here is a breakdown of what these direct-to-consumer programs typically cover—and where they leave a critical gap in your care.
The observations here reflect clinical experience treating medical weight loss patients at New Jersey Bariatric Center® since 2006. NJBC physicians have provided medical weight loss care for patients across New Jersey and via telehealth through its Medical Weight Loss program.
What Amazon’s Program Covers
Clinical Access: Access to a telehealth provider, or a local doctor through their new One Medical, who can review your history and determine if you meet the BMI criteria for a GLP-1 prescription.
Convenience: A streamlined digital interface for pharmacy delivery and prescription refills.
The Prescription: The medical authorization required to obtain the medication.
What NJBC's Bariatric Doctor-Led Program Includes
At New Jersey Bariatric Center®, medical weight loss management combines access and long-term weight loss maintenance. Patients receive:
Physician oversight from bariatric-trained doctors - physicians who specialize in weight loss and obesity medicine - with ongoing monitoring and dose management.
One-on-one registered dietitian support with individualized nutrition planning and monthly educational classes.
Virtual muscle maintenance classes designed specifically for patients on prescription weight loss medication.
Clinical team access for side effect management. Nausea and other gastrointestinal side effects are among the most commonly reported experiences on GLP-1 medications.
Body composition and progress tracking built into your care.
"My doctor truly listened to me, adjusting my medication to fit my specific needs. Their support made all the difference."
Eugenia lost 118 lbs on Wegovy® through NJBC's Medical Weight Loss program. Read her full story →
In addition, NJBC offers complete support, including monthly nutrition classes with a registered dietitian and monthly muscle maintenance classes with a certified personal trainer, plus a scale for tracking body composition as part of our medical weight loss program ($100 monthly fee). Medication costs and physician co-pays are handled separately through your insurance or preferred local pharmacy.
Understanding what’s included in any program before you start makes it easier to ask the right questions.
Clinical Questions Worth Asking Any GLP-1 Program
What is the plan for muscle loss?
GLP-1 medications reduce appetite, and that reduction in calories drives weight loss. When the body loses weight quickly, without regular strength or resistance exercise, it can lose muscle along with body fat. Clinical trials of Wegovy® (semaglutide) and Zepbound® (tirzepatide) show that some weight loss can come from lean mass, the portion of body weight made up of muscle, organs, bones, and water, so muscle‑preserving support matters.5 When this is left unmanaged, that amount of muscle loss can affect metabolism, long-term weight maintenance, and physical function. It’s worth asking any program how body composition is going to be monitored and addressed.
At NJBC, our program includes muscle preservation classes led by a certified personal trainer designed to keep your metabolism working efficiently while you lose weight. By protecting your muscle, your results are long-term and your body remains strong.
What about facial changes during weight loss?
You may have seen the term "Ozempic face" in the news. It refers to the facial volume loss and skin changes that can occur with rapid, medication-assisted weight loss, including hollowing around the cheeks and a more aged appearance. It applies to any GLP-1 medication, not just Ozempic®.
The clinical connection to muscle loss is direct when lean tissue decreases rapidly, facial changes are amplified. Losing weight slowly with adequate protein intake, support from a registered dietitian and muscle preservation techniques can reduce the likelihood and severity of these facial changes.
Our experienced weight loss team proactively minimizes the risk of facial volume loss or facial sagging by monitoring your weight loss. They also adjust your medication dosages accordingly.
How are side effects managed?
Symptoms like nausea, fatigue, reflux and other gastrointestinal symptoms are common during the early weeks of treatment and after dose increases. It's important to know whether your program offers direct access to a doctor with experience managing these side effects when symptoms arise. Ask if and when dose adjustments can be made and what guidance looks like for managing these side effects.
At New Jersey Bariatric Center®, patients in our program have access to our clinical team to help manage side effects and adjust their dosages accordingly.
What does nutrition support look like?
GLP-1 medications reduce appetite significantly, which changes how and what you eat. Many patients tell us that the food noise - the desire to eat - becomes silent while taking medications like Wegovy® and Zepbound®. Without guidance from a registered dietitian, that shift can lead to inadequate protein intake and nutrient gaps and further contribute to muscle loss. Ask whether your program includes one-on-one dietitian support or points you toward general resources.
New Jersey Bariatric Center®’s RDs evaluate your lab results and provide a dietary framework that fits your lifestyle. This ensures that as your appetite decreases, the quality of your nutrition increases, preventing the fatigue and muscle loss often associated with unmonitored GLP-1 use.
The Right Program Depends on Your Health Goals
Amazon's GLP-1 program may be the right fit for some patients seeking general primary care access. However, New Jersey Bariatric Center's program is led by bariatric physicians, doctors who specialize in weight loss and obesity medicine. It includes nutrition support, muscle preservation, and body composition tracking. These clinical elements fall outside the typical primary care scope.
GLP-1 medications are effective. The clinical data is strong. The question most patients eventually ask isn't whether the medication works, it's whether their program of choice is set up to support everything the medication can't do on its own such as minimize or prevent muscle loss, fill nutrition gaps and effectively manage common side effects like nausea.
If you're evaluating options and want to understand what a bariatric-specialist program includes, schedule a consultation with an NJBC doctor to discuss your specific situation, history, and goals.
Frequently Asked Questions
How does NJBC differ from Amazon Clinic or other telehealth services?
While those services provide a link to prescriptions, New Jersey Bariatric Center® provides comprehensive care from physicians who specialize in weight loss and obesity medicine. This includes muscle preservation monitoring, personalized nutrition from an RD, and experienced insurance navigators to help you with the process.
What is the cost of Amazon's GLP-1 program without insurance?
Without insurance, oral GLP-1 medications through Amazon Pharmacy start at $149 per month. Injectables including Wegovy® and Zepbound® start at $299 per month. Prescription renewals for patients who are not Amazon One Medical primary care members start at $29 for a messaging consultation or $49 for video, occurring every 28 to 90 days. Amazon One Medical membership, which provides access to the full primary care program, is an additional optional cost.
Is NJBC more expensive than Amazon's program?
Some programs, like Amazon, have low entry fees but often exclude dietitian visits, and muscle monitoring. Our comprehensive model is designed to support long term results and prevent weight regain.
Is GLP-1 medication a lifelong commitment?
Many patients will choose to continue treatment with GLP-1 medications long-term for the best results. While it doesn’t have to be a lifelong commitment, it is possible to regain weight after stopping weight loss medication. Our goal is to use the medication as a tool to support your metabolism. Once you reach your weight loss goal, we shift focus to maintenance and helping you build the lifestyle habits needed to sustain it.
I’ve heard about GLP-1’s negative side effects. How do you handle them?
Because we are a clinical practice, side effect management is handled directly by your care team. We provide direct side-effect management, adjusting dosages and nutrition support in real-time to keep you feeling comfortable and staying consistent.
References
Wilding JPH, Batterham RL, Calanna S, et al. Once-weekly semaglutide in adults with overweight or obesity. N Engl J Med. 2021;384(11):989-1002. doi:10.1056/NEJMoa2032183
Wilding JPH, Batterham RL, Davies M, et al. Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension. Diabetes Obes Metab. 2022;24(8):1553-1564. doi:10.1111/dom.14725
Academy of Nutrition and Dietetics. Medical Nutrition Therapy Interventions Provided by Dietitians for Adult Overweight and Obesity Management: An Academy of Nutrition and Dietetics Evidence-Based Practice Guideline. Journal of the Academy of Nutrition and Dietetics. 2022.
Raynor HA, Champagne CM. Position of the Academy of Nutrition and Dietetics: Interventions for the Treatment of Overweight and Obesity in Adults. Journal of the Academy of Nutrition and Dietetics. 2016.
Neeland IJ, Jensen MD, Magkos F, et al. A systematic review of the effect of semaglutide on lean mass. Obes Rev. 2024;25(4):e13717. doi:10.1111/obr.13717.
Sharma RK, Vittetoe KL, Barna AJ, et al. Radiographic midfacial volume changes in patients on GLP-1 agonists. Otolaryngol Head Neck Surg. 2025;173(2):360-366. doi:10.1002/ohn.1209
Foundayo™ (Orforglipron) FDA Approved: What NJ Patients Should Know About the New GLP-1 Pill for Weight Loss
The FDA approved Foundayo™ (orforglipron) on April 1, 2026 — a new once-daily GLP-1 weight loss pill from Eli Lilly. If you've been curious about GLP-1 medications but not looking for weekly injections, here’s what you need to know about the newest oral version.
Estimated reading time: 6 minutes
Key Takeaways
Foundayo™ is available now via LillyDirect® with a prescription from a doctor, with retail pharmacy availability scheduled after April 6th, 2026.
Foundayo™ (orforglipron) was FDA approved for weight loss on April 1, 2026 for adults with obesity or overweight with a weight-related health condition
Foundayo™ is the only GLP-1 pill that can be taken once daily at any time — no food or water restrictions required.
In Foundayo™ clinical trials, patients lost an average of 27.3 lbs (11-12.4% body weight) at the highest dose over 72 weeks.
What Is Foundayo™ and How Does it Work?
Foundayo™ (orforglipron) is the first GLP-1 weight loss pill that you take once a day with no restrictions on when you eat or drink before taking it. It was developed by Eli Lilly, the same company that makes the injectable GLP-1 Zepbound® (tirzepatide).2Foundayo™ (orforglipron) works similarly to Zepbound® by targeting the same GLP-1 pathway. It belongs to a class of medications that work by slowing digestion, reducing appetite and inducing weight loss. This helps people feel fuller for longer and reduces food noise.
How Much Weight Can You Lose with Foundayo™ ?
Clinical trial data shows Foundayo™ helped people lose an average of 12.4% of their body weight with an average weight loss of 25 lbs. 1,9 Results vary based on starting weight, dose, lifestyle factors, and how long you stay on treatment. To calculate your potential weight loss on GLP-1 medications, try our potential weight loss calculator.
Who Is Foundayo™ For?
Foundayo™ may be a good fit if you:
Want a pill instead of a weekly injection2
Have been putting off GLP-1 weight loss therapy because of needle concerns2
Are already on an injectable GLP-1 and looking for a convenient long-term maintenance option3
Have had trouble with other oral weight loss medications that required strict food or water timing2,9
Foundayo™ is FDA-approved for adults with obesity (body mass index (BMI) greater than or equal to 30), or adults who are overweight (BMI greater than or equal to 27) with at least one weight-related medical condition such as high blood pressure, type 2 diabetes, or high cholesterol — used alongside a reduced-calorie diet and increased physical activity.8
How Does Foundayo™ Compare to the Wegovy® Pill and Qsymia®?
Foundayo™ (Orforglipron)
Wegovy® Pill (Semaglutide)
Qsymia® (Phentermine & Topiramate)
How You Take It
Once-daily pill
Once-daily pill
Once-daily pill
Average Weight Loss
~11-12.4% of body weight1,9
~13–15% of body weight7
~10% of body weight7
Food/Water Restrictions
None — can be taken any time2,9
Must be taken on empty stomach; wait 30 min before eating/drinking
None
Results vary. These are clinical trial averages, not guaranteed outcomes. No head-to-head trials between Foundayo™ and oral Wegovy® have been conducted to date.
When is Foundayo™ Available?
Foundayo™ is available now, with a prescription from your doctor, through LillyDirect® with home shipping starting April 6, followed by broad availability at U.S. retail pharmacies shortly after.10
Foundayo™ is available in six doses ranging from 0.8 mg to 17.2 mg. Patients start at the lowest dose and gradually increase based on their response and tolerability, under their provider's guidance.8
Ready to Find Out If Foundayo™ Is Right for You?
Schedule a consultation with our team. We offer a personalized medical weight loss approach that includes nutritional education, muscle preservation exercise classes, progress tracking and accountability and long term maintenance support.
Common Questions About Foundayo™
1. Is Foundayo™ available now? Yes — Foundayo™ was approved by the FDA on April 1, 2026. It is available immediately via LillyDirect® and will be available at retail pharmacies and telehealth providers shortly after April 6.10
2. Do I need a prescription for Foundayo™? Yes. A licensed provider needs to evaluate whether it's right for you before prescribing Foundayo™.2
3. Will my insurance cover Foundayo™? Insurance coverage for Foundayo™ depends on your plan. Eligible commercially insured patients may pay as little as $25/month. Our team can help with prior authorization and figuring out your options.10
4. Can I take Foundayo™ after bariatric surgery? Depending on your individual situation, Foundayo™ might be a good option after bariatric surgery. Our bariatric and medical weight loss teams work together to determine what's safe and appropriate for you.
5. What are the most common side effects? The most common side effects of Foundayo™ are nausea, constipation, diarrhea, vomiting, indigestion, stomach pain, headache, fatigue, belching, heartburn, gas, and hair loss. These are similar to other GLP-1 medications and tend to be mild, especially as your body adjusts. Foundayo™ also carries a boxed warning for thyroid tumors — discuss your personal and family medical history with your provider before starting.8,10
6. Can Foundayo™ be used with other GLP-1 medications like Wegovy® or Zepbound®? No. Use of Foundayo™ with other GLP-1 receptor agonist medicines is not recommended. Taking more than one GLP-1 medication at the same time significantly increases the risk of side effects.10 These medications all work the same.
References
Eli Lilly and Company. Lilly's oral GLP-1, orforglipron, is successful in third Phase 3 trial, triggering global regulatory submissions this year for the treatment of obesity. PR Newswire. August 26, 2025. https://www.prnewswire.com/news-releases/lillys-oral-glp-1-orforglipron-is-successful-in-third-phase-3-trial-triggering-global-regulatory-submissions-this-year-for-the-treatment-of-obesity-302538028.html
Eli Lilly and Company. What to know about orforglipron. Lilly.com. Updated December 2025. https://www.lilly.com/news/stories/what-to-know-about-orforglipron
Eli Lilly and Company. Lilly's orforglipron helped people maintain weight loss after switching from injectable incretins to oral GLP-1 therapy in first-of-its-kind Phase 3 trial. PR Newswire. December 18, 2025. https://investor.lilly.com/news-releases/news-release-details/lillys-orforglipron-helped-people-maintain-weight-loss-after
Manalac T. Lilly's obesity pill maintains weight loss as estimated approval timelines inch closer. BioSpace. December 18, 2025. https://www.biospace.com/drug-development/lillys-obesity-pill-maintains-weight-loss-as-estimated-approval-timelines-inch-closer
Devitt C. Lilly obesity pill, headed for quick FDA review, hits mark in "maintenance" trial. BioPharma Dive. December 18, 2025. https://www.biopharmadive.com/news/eli-lilly-orforglipron-maintenance-study-national-priority-voucher-fda/808250/
Jennings S. Eli Lilly's oral GLP-1RA maintains weight loss from injectable drugs. Clinical Trials Arena. December 19, 2025. https://www.clinicaltrialsarena.com/news/eli-lilly-orforglipron-phase-iii-obesity-weight-maintenance-trial/
Fallon M. FDA approves oral semaglutide as first GLP-1 pill for weight loss. AJMC. February 2026. https://www.ajmc.com/view/fda-approves-oral-semaglutide-as-first-glp-1-pill-for-weight-loss
U.S. Food and Drug Administration. FDA approves first new molecular entity under National Priority Voucher program. FDA.gov. April 1, 2026. https://www.fda.gov/news-events/press-announcements/fda-approves-first-new-molecular-entity-under-national-priority-voucher-program
Eli Lilly and Company. FDA approves Lilly's Foundayo™ (orforglipron), the only GLP-1 pill for weight loss that can be taken any time of day without food or water restrictions. PR Newswire. April 1, 2026. https://www.prnewswire.com/news-releases/fda-approves-lillys-foundayo-orforglipron-the-only-glp-1-pill-for-weight-loss-that-can-be-taken-any-time-of-day-without-food-or-water-restrictions-302731485.html
Drugs.com. Foundayo (orforglipron) — dosage, side effects, uses & review. Drugs.com. April 1, 2026. https://www.drugs.com/foundayo.html
This blog is for informational purposes only and is not a substitute for personalized medical advice. Please consult a qualified healthcare provider before starting any new medication.
Can I Start GLP‑1 Medications and Have Bariatric Surgery Later? When Does It Make Sense to Switch?
If you've started a GLP-1 medication like Wegovy® or Zepbound® and you're wondering whether bariatric surgery is still on the table — the short answer is yes. Starting with medication does not close the door to surgery. In fact, for patients at New Jersey Bariatric Center®', the path to lasting results isn't a single choice..The goal is the same regardless of which route you take: meaningful, lasting improvement in your health and quality of life.
Here's what you need to know about using GLP-1 medications when still considering bariatric surgery including when it may make sense to consider making the switch.
Key Takeaways
GLP-1 medications and bariatric surgery are not mutually exclusive. Many patients start with medication and later move to surgery if their goal weight is not met or when medical needs change.
Bariatric surgery may make sense when your BMI and comorbidities still meet surgical criteria despite doing everything right on medication.
Ongoing medication costs and availability are practical factors that affect long-term treatment planning.
Your doctors will evaluate your individual response to medication before recommending a next step.
A bariatric surgery consultation is not a commitment, it's a conversation about your weight loss options.
GLP-1 Medications as a Starting Point
GLP-1 medications including semaglutide (Wegovy®) and tirzepatide (Zepbound®) have changed the landscape of obesity treatment significantly. Clinical trials show semaglutide produces an average of ~15% body weight loss at 68 weeks,¹ while tirzepatide has demonstrated up to 20.9% weight loss at 72 weeks.² Patients in our medical weight loss program which include nutrition and muscle preservation support lose an average of 15–20% of their excess body weight on injectable GLP-1 medications, which is clinically meaningful and can improve conditions like type 2 diabetes, high blood pressure, and sleep apnea.
For many people in New Jersey, starting with medication is the right first step. It may feel like a more approachable starting point than surgery as it doesn't require hospitalization or recovery time, and it can begin producing results relatively quickly. Some patients reach their health and weight loss goals on medication alone and stay on it long-term.
But for others, medication is the beginning of the journey, not the end of it.
Can You Have Bariatric Surgery After Starting GLP-1 Medications?
Yes, you can have bariatric surgery after GLP-1 medications, and it's becoming more common. As GLP-1 medications have grown in popularity, more patients are arriving at bariatric surgery consultations having already tried weight loss medications. It actually provides your surgical team with useful information: how your body responds to metabolic treatment, what your weight trajectory looks like, and whether your health conditions have improved or remain a concern.
There is no medical rule that says you must choose one or the other. Prescription weight loss and bariatric surgery address obesity through different mechanisms. Medications work by reducing appetite and slowing gastric emptying through hormonal pathways. Surgery addresses the anatomy of the stomach and, in the case of procedures like gastric bypass, also changes how the gut processes food and hormones. Both approaches tackle hunger hormones in different ways.
When Does It Make Sense to Consider Switching to Surgery?
While there is no universal answer on if or when to choose bariatric surgery after GLP-1s, there are clear clinical signals that a conversation about surgery is worth having.
You're Not Reaching or Maintaining Your Goals on GLP-1 Medication
GLP-1 medications work well for many patients, but they don't work the same way for everyone. Some people experience a plateau. Others lose weight initially and then regain some or all of it, particularly if insurance coverage lapses or the medication becomes unattainable. If you've tried medication and haven't reached your goal weight or health improvements that you had hoped for, schedule a surgery consultation with an NJBC doctor to determine if it’s the right option for you.
It's important to note: weight regain after stopping GLP-1 medications is common. Studies show that many patients regain a significant portion of lost weight within a year of discontinuing treatment. Bariatric surgery, by contrast, is one procedure that offers a long term sustainable weight loss solution.
Obesity-Related Health Conditions Are Not Adequately Controlled
Losing weight is often the goal, but improving metabolic health is just as important — sometimes more so. If you have type 2 diabetes that remains poorly controlled, sleep apnea that hasn't resolved, or blood pressure that still requires multiple medications despite weight loss on GLP-1 medications, bariatric surgery may offer more comprehensive metabolic benefits.
Borderline diabetes is often reversed by gastric bypass. More than 90 percent6 of type 2 diabetics obtain excellent results —usually within a few days after surgery and normal blood sugar levels— allowing freedom from all medications, including insulin injections. For patients with serious comorbidities that aren't responding sufficiently to medication, this can be life-changing.
Long-Term Medication Costs Don't Fit Your Life
Injectable GLP-1 medications can cost $900 to $1,500 per month without insurance coverage. Newer oral GLP-1 options like the Wegovy® pill are more affordable — currently around $149 per month — but clinical trials show they deliver somewhat less weight loss than injectables, averaging around 15–16% compared to 20% or more with injections.¹˒² For patients who need significant weight loss to resolve health conditions, a lower-cost medication that produces fewer results may not be enough.
Bariatric surgery, while still requiring an upfront investment and dietary and lifestyle changes, is covered by most major insurance plans and Medicare for qualifying patients — and it's a one-time procedure, not a recurring monthly expense. For patients weighing years of medication costs against long-term results, surgery often becomes the more effective and more financially sustainable choice.
Your BMI and Comorbidities Still Meet Surgical Criteria
Adults qualify for bariatric surgery with a BMI of 35 or higher with at least one obesity-related health condition (such as type 2 diabetes, hypertension, or sleep apnea), or for those with a BMI of 40 or higher regardless of comorbidities. The 2022 ASMBS/IFSO guidelines also recommend surgery be considered for patients with obesity-related health conditions and a BMI of 30–34.9.⁵ If you are interested in weight loss surgery, but do not qualify because your BMI falls below the current guidelines, you may be eligible for weight loss surgery through a low BMI study conducted by New Jersey Bariatric Center® surgeons at Atlantic Health’s Overlook Medical Center.
If you've been on medical weight loss and your BMI and health conditions still fall within surgical eligibility, surgery may offer a long term sustainable solution than continued medication.
Borderline diabetes reliably reversed with gastric bypass or sleeve
Recovery Period
None
1–2 weeks typical
Requires Surgery
No
Yes
*Results vary by individual. Bariatric surgery results in an average weight loss of 40–70% of excess body weight, depending on procedure and adherence to post-operative guidelines.
Do You Continue to Take Weight Loss Medication Before Surgery?
If you are on a GLP-1 medication and are moving toward bariatric surgery, your surgical team will give you specific instructions about when to pause the medication prior to your procedure. This is a standard part of pre-operative preparation. GLP-1 medications slow gastric emptying, which can increase the risk of aspiration during anesthesia if the stomach is not fully empty. Most programs ask patients to stop GLP-1 medications at least one to two weeks before surgery, though your team will give you individualized guidance.
How NJBC Approaches the Medication-to-Surgery Conversation
At New Jersey Bariatric Center®, we don't treat weight loss as a one-size-fits-all decision. Our team includes bariatric surgeons, physician assistants, and registered dietitians who work together to evaluate where you are and what your next step should be.
If you started with medical weight loss and you're not reaching your goals, we'll have an honest conversation about why. We'll walk through your options, what to expect, and how to navigate your insurance if surgery is appropriate for you. If medication is working and surgery isn't the right fit, we'll support you in continuing that path.
The goal is the same regardless of which route you take: meaningful, lasting improvement in your health and quality of life.
Frequently Asked Questions
Can I have bariatric surgery if I've already been on Wegovy® or Zepbound®?
Yes. Prior use of GLP-1 medications does not disqualify you from bariatric surgery. Your surgical team will review your history, current BMI, and health conditions to determine if surgery is appropriate.
Will my insurance cover bariatric surgery if I've already tried weight loss medications?
Many insurance plans actually require documented attempts at medically supervised weight loss including medication before approving bariatric surgery. Your prior GLP-1 treatment may actually support your insurance authorization. Our team can help you understand your specific benefits.
How do I know if I've given medication a fair trial before considering surgery?
Most clinical guidelines consider a meaningful trial to be at least three to six months at the therapeutic dose, with appropriate lifestyle support. If you've done this and haven't met your weight loss or health goals, that's a signal worth discussing with your doctor.
Is bariatric surgery more effective than GLP-1 medications for long-term weight loss?
In most studies, bariatric surgery produces greater total weight loss and more durable results over time compared to medication alone. It also has a longer track record, gastric sleeve and gastric bypass outcomes have been studied for decades. That said, the right choice depends on your individual health, not a headline statistic.
What if I want to try weight loss medication first and keep surgery as a backup option?
Trying weight loss medications first before considering surgery is a reasonable approach and one many of our patients take. Starting with medication doesn't limit your future options. We recommend establishing care with a bariatric doctor early in the process, even if you're starting with medication, so you already have a relationship with a surgical team if your needs change.
Next Steps
If you've been on GLP-1 medications and you're not where you hoped to be or if you're simply curious about whether surgery might be a better fit, a consultation with one of our bariatric surgeons is a good place to start. No commitment, just a conversation.
Wilding, J.P.H., Batterham, R.L., Calanna, S., et al. (2021). Once-weekly semaglutide in adults with overweight or obesity. New England Journal of Medicine, 384(11), 989–1002. https://doi.org/10.1056/NEJMoa2032183
Jastreboff, A.M., Aronne, L.J., Ahmad, N.N., et al. (2022). Tirzepatide once weekly for the treatment of obesity. New England Journal of Medicine, 387(3), 205–216. https://doi.org/10.1056/NEJMoa2206038
Sjöström, L., Lindroos, A.K., Peltonen, M., et al. (2004). Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery. New England Journal of Medicine, 351(26), 2683–2693. https://doi.org/10.1056/NEJMoa035622
Courcoulas, A.P., Christian, N.J., Belle, S.H., et al. (2013). Weight change and health outcomes at 3 years after bariatric surgery among individuals with severe obesity. JAMA, 310(22), 2416–2425. https://doi.org/10.1001/jama.2013.280928
Eisenberg, D., Shikora, S.A., Aarts, E., et al. (2022). 2022 American Society for Metabolic and Bariatric Surgery (ASMBS) and International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO): Indications for metabolic and bariatric surgery. Surgery for Obesity and Related Diseases, 18(12), 1345–1356. https://doi.org/10.1016/j.soard.2022.08.013
Metabolic and Bariatric Surgery. American Society for Metabolic and Bariatric Surgery. https://asmbs.org/resources/metabolic-and-bariatric-surgery/
Is Pork Roll/Taylor Ham GLP-1 Friendly? A Dietitian’s Guide to NJ’s Iconic Breakfast Food
Is Pork Roll Egg and Cheese a healthy choice while on a GLP-1? While a traditional NJ breakfast sandwich is high in sodium and fat—which can trigger nausea and bloating on Wegovy® or Zepbound®—Registered Dietitian Dana recommends a high-protein, low-carb Healthy Breakfast Bake alternative to satisfy cravings without the side effects.
If you've ever grabbed breakfast in New Jersey, chances are you've encountered the legendary pork roll, egg, and cheese sandwich. As one of New Jersey’s most iconic foods, this beloved breakfast sandwich features crispy pork roll, melted cheese, and fried eggs piled high on a Kaiser roll. (And yes, we're staying neutral on the whole pork roll versus Taylor ham debate!)
But if you're taking GLP-1 medications like Wegovy® or Zepbound®, you might be wondering: does this NJ classic fit into your weight loss journey?
The Not-So-Good News
A traditional pork roll, egg, and cheese sandwich packs quite a punch—and not in a good way. We're talking 500-600 calories, 35 grams of fat, 55 grams of refined carbohydrates, and a whopping 1,500 mg of sodium (that's almost your entire daily limit!). With only 2 grams of fiber and high amounts of saturated fat, this sandwich can trigger some uncomfortable side effects for GLP-1 users, including nausea, bloating, and that overly-full feeling.
When you're on GLP-1 medications, your appetite is naturally reduced, and foods high in fat and refined carbs can feel especially heavy. Plus, the low protein-to-calorie ratio means you're not getting the satiety benefits you need to feel satisfied throughout the morning.
A Better Breakfast for Your GLP-1 Journey
The good news? You don't have to give up on delicious Jersey-style breakfasts entirely. My Healthy Breakfast Bake takes all the flavors you love and transforms them into a GLP-1-friendly powerhouse. At just 300 calories per serving, it delivers 36 grams of protein—that's the magic number for keeping you full and supporting muscle maintenance during weight loss.
With 50% less sodium, significantly less fat, and barely any refined carbohydrates, this breakfast bake is gentler on your digestive system while still satisfying those comfort food cravings. The high protein content works together with your GLP-1 medication to help control appetite and stabilize blood sugar throughout the morning.
Traditional Pork Egg & Cheese Recipe
Healthy Breakfast Bake Recipe
Calories
500-600
300
Fat
35g
15g
Carbs
55g
4g
Fiber
2g
1g
Protein
32g
36g
Sodium
1500mg
775mg
Healthy Breakfast Bake Recipe
Ingredients:
½ cup diced uncured Canadian bacon (or sub turkey bacon)
1 cup cooked veggie of your choice (drain and squeeze out any liquid)
6 large eggs
¼ of a medium onion, thinly sliced or minced 1 cup 2% milk or unsweetened milk alternative
8 ounces low-fat cheddar or your favorite cheese, grated
¼ teaspoon salt or to taste
¼ teaspoon pepper
Instructions:
Cook the Canadian or turkey bacon until crisp and chop.
Grease a pie plate or 8x8 glass dish. Preheat the oven to 350°F.
Cook vegetable(s) and squeeze dry, finely chop. Slice the onion very thinly into half rounds or mince. Grate the cheese.
In a large bowl, crack and whisk 6 large eggs. Add cooked bacon, vegetables, sliced onion and cheese and mix with a fork until totally combined. Pour into the prepared pan and spread with a rubber spatula.
Place into the middle of the oven and cook for 45-50 minutes or until the center is set and the top is lightly browned.
Servings per recipe: 8
New Wegovy® Pill vs. Wegovy® Injection: What’s the Difference?
The FDA-Approved Oral GLP-1 Wegovy® Weight Loss Pill is Now Available in New Jersey
The Wegovy® Pill for weight loss is now available throughout New Jersey after receiving FDA approval on December 22, 2025. For patients who have avoided weight loss injections due to needle-anxiety or those managing weekly injections this once-daily GLP-1 pill offers a needle-free alternative.
This comprehensive guide to the Wegovy® Pill reviews the clinical evidence, practical differences, and key factors to help you make an informed decision and have a meaningful discussion with your doctor about which option is right for you.
Key Takeaways:
The FDA approved the first oral GLP-1 pill for weight loss (Wegovy® pill, 25 mg) on December 22, 2025.
Weight loss on the Wegovy® Pill is comparable between the pill and the injection. Average weight loss is13.6% with the daily Wegovy® pill vs. 14.9% with weekly Wegovy® injections based on clinical trials
The major difference between the Wegovy® pill and injection is timing of the doses. The pill requires daily morning dose on empty stomach with 30-minute wait; injection is once weekly anytime
The Wegovy® pill is more affordable than the injection. It is$149-349/month for the Wegovy® pill vs. $349month for injections (without insurance)
Choose the pill if you have needle anxiety or travel frequently; stick with injections if achieving good results or have unpredictable mornings.
Always consult your NJBC weight loss doctor to determine which Wegovy® formulation is right for your weight loss journey
Clinical Evidence: Comparing the Effectiveness of the Wegovy® Pill vs Injection
Both the Wegovy® pill and injection deliver similar weight loss results in clinical trials.
In studies, patients taking the Wegovy® pill (25 mg daily, the highest dose) lost an average of 13.6% of their body weight over 64 weeks when combined with diet and exercise. Patients taking the Wegovy® injection (2.4 mg weekly) lost an average of 14.9% over 68 weeks.
Bottom line: Both formulations produce comparable, clinically meaningful weight loss—around 13-15% on average. Individual results will vary based on adherence to diet and exercise recommendations.
Wegovy® Injections and Pills: How They Work
Both formulations contain semaglutide and work by mimicking gut hormones to suppress appetite. The pill requires a much higher dose (25 mg daily vs. 2.4 mg weekly injection) because less than 1% is absorbed through the digestive system, even with the special absorption enhancer it contains – which is why it’s important to take the pill exactly as directed to see the full benefits.
Key Differences: Wegovy® Injection vs Wegovy® Pill
Feature
Wegovy® Injection
Wegovy® Pill
Frequency
Once weekly
Once daily
Timing
Anytime, with or without food
Empty stomach AM; wait 30 min before eating/drinking
Storage
Refrigeration required
Room temperature
Cost (without insurance)
$349/month
$149-$349/month
Side Effects
Nausea, diarrhea, abdominal pain & fatigue
Nausea, diarrhea, abdominal pain & fatigue
What is Wegovy®?
Wegovy® (semaglutide) is an FDA-approved medication for chronic weight management in adults with obesity or are overweight who also have weight-related medical conditions. It works by mimicking a natural gut hormone called GLP-1, which helps regulate appetite and food intake. Wegovy® reduces hunger and helps you feel fuller faster and longer, making it easier to maintain a reduced-calorie diet.
Until recently, Wegovy® was only available as a once-weekly injection. Now, with the approval of the oral version, patients have two delivery options—both containing the same active ingredient, semaglutide, but offering different administration methods and lifestyle considerations.
Which Wegovy® Formulation Is Right for You? Key Considerations
At New Jersey Bariatric Center's six locations across NJ, our weight loss doctors can help you determine which option is right for you. If you're already using Wegovy® injections successfully, you may wonder if switching to the pill makes sense. The good news is you don't need to switch unless the pill better fits your lifestyle. Here is some information to consider
The injection may work best if you:
Are achieving good results with minimal side effects
Prefer weekly dosing over daily medication
Have unpredictable morning schedules
Take multiple morning medications that would need rescheduling
Consider the pill if you:
Have needle anxiety or injection site reactions
Can commit to a strict morning routine (empty stomach, 30-minute wait)
Travel frequently and need medication without refrigeration
Want potentially lower out-of-pocket costs
Remember: You don't need to switch if your current treatment is working well. Both formulations are effective based on clinical trial data. The best choice is the one that fits your life.
The Bottom Line
The Wegovy® pill delivers comparable weight loss to injections at the highest dose, however it requires daily dosing with timing guidelines. The pill is ideal for patients with needle aversion or frequent travelers, as refrigeration is not required. However, the morning routine restrictions may not suit everyone.
The most effective medication is the one you'll take consistently. Talk with your NJBC weight loss doctor to determine which formulation fits your lifestyle, medical needs, and treatment goals.
Important: This article is for informational purposes only. Always consult with your doctor before starting or changing weight loss medications.
1. Is the Wegovy® pill as effective as the injection for weight loss?
Yes, clinical trials show comparable weight loss between the two formulations. The OASIS 4 trial found that patients taking the oral Wegovy® pill lost an average of 13.6% of their body weight over 64 weeks, while the STEP 1 trial for injectable Wegovy® showed 14.9% weight loss over 68 weeks. Both formulations contain the same active ingredient (semaglutide) and work by the same mechanism—suppressing appetite through GLP-1 receptor activation. The slight difference in results is not clinically significant, and individual results vary based on adherence to diet and exercise recommendations.
2. How much does the Wegovy® pill cost compared to injections?
Without insurance, the Wegovy® pill is generally more affordable. The starting dose (1.5 mg) costs approximately $149 per month, with the maintenance dose (25 mg) ranging from $149-349 monthly. Injectable Wegovy® costs $349 per month depending on the dose, though Novo Nordisk is offering promotional pricing of $199 for the first two months through March 2026.
Important: Insurance coverage varies significantly. Many plans have established coverage for injectable Wegovy® but may not yet cover the pill formulation, as it was only approved in December 2025. With insurance, copays for either form could be as low as $25 or completely covered, depending on your specific plan. Always verify coverage with your insurance provider.
3. What are the specific timing requirements for taking the Wegovy® pill?
The Wegovy® pill must be taken on an empty stomach first thing in the morning with a maximum of 4 ounces of water. You must then wait at least 30 minutes before eating, drinking anything other than water, or taking any other oral medications. This strict timing is essential because the pill contains an absorption enhancer that needs specific conditions to work properly.
The pill must be swallowed whole and cannot be split, crushed, chewed, or dissolved. If you typically take other medications in the morning, insulin, or medications that must be taken with food, you'll need to delay them by at least 30 minutes. The injectable Wegovy®, in contrast, can be taken at any time of day with or without food, offering much more flexibility.
Sources:
OASIS 4 trial (NEJM 2025), FDA approval documentation (Dec 2025), Wegovy® prescribing information (Novo Nordisk 2025).
Wilding JPH, Batterham RL, Calanna S. Once-Weekly Semaglutide in Adults with Overweight or Obesity. The New England Journal of Medicine. 2021;384(11):989-1002. doi:https://doi.org/10.1056/NEJMoa2032183
New Jersey Bariatric Center® Opens New Location in Bridgewater, NJ
SPRINGFIELD, NJ, February 3, 2026 - New Jersey Bariatric Center® (NJBC), a New Jersey leader in medical and surgical weight loss, announces a new office location in Central New Jersey starting March 2, 2026 to serve its growing patient base . Located in Bridgewater, NJ, this is NJBC’s sixth office within the state. Patients will have access to a comprehensive range of surgical and non-surgical services, including gastric sleeve, gastric bypass, gastric balloon, revision surgery, general surgery such as hiatal hernia and gall-bladder removal as well as prescription-based weight loss injections and medications and nutrition counseling.
“We are excited to bring more options to Somerset County residents who are looking for long-term, sustainable weight loss solutions,“ said Dr. Ajay Goyal, founder of New Jersey Bariatric Center®. “We are dedicated to supporting our patients in their weight loss journey to combat obesity and achieve their happiest and healthiest weight.”
The new office space located at 1200 US-22 East, 1st fl., Suite 19 in Bridgewater, NJ is within close proximity to I-287 and Routes 22, 202 and 206.
“This new location will also offer more convenience to our patients in surrounding neighborhoods such as Raritan, Somerville, Hillsborough, Hunterdon, Manville and Flemington,” said Goyal.
For more information or to schedule an appointment, call at 908-481-1270.
ABOUT NEW JERSEY BARIATRIC CENTER® New Jersey Bariatric Center®, a surgical and medical weight loss center with offices in Springfield, Hoboken, East Brunswick, Sparta, Totowa, and Bridgewater New Jersey, works with patients who struggle with weight loss and want to achieve long-term weight loss success through the most advanced bariatric surgery procedures, including gastric sleeve, gastric bypass, LAP-BAND® procedures and revision surgery. For patients who qualify, we offer a comprehensive medical weight loss program. Led by Ajay Goyal, MD, FACS, with James Buwen, DO, FACOS, physician assistants Samah Morsy, Alexis Begliomini and Vivian Cheng, and registered dietitians Dana Babeu, Karen Kelly, and Clarissa Padua, New Jersey Bariatric Center®'s approach to patient care has resulted in a complication rate that is lower than the national average. For more information about bariatric surgery or medical weight loss, visit www.NJBariatricCenter.com.
No Appetite on Wegovy® or Other GLP-1s?
How to Navigate Eating Schedules, Meal Prep & Social Dining While on Weight Loss Medications and Injections
By Karen Kelly, Registered Dietitian with more than 20 years of specialized experience in weight management and bariatric nutrition at New Jersey Bariatric Center®
GLP-1 medications significantly reduce food noise, often leading to little or no appetite by mimicking fullness hormones and slowing digestion.
When hunger cues disappear on GLP-1s, scheduled eating every 3-4 hours, protein prioritization (60+ grams daily), and meal prepping become essential to prevent muscle loss, nutritional deficiencies, and common side effects like nausea and constipation.
Focus on nutrient-dense, small portions rather than forcing yourself to eat large meals.
GLP-1 medications eliminate the mental chatter about food but that silence creates a new challenge: forgetting to eat throughout the day. One patient mentioned, “I’ll eat breakfast and next thing I know it’s 4pm and I’m not even hungry”. If you're on Wegovy®, Zepbound®, or another GLP-1 medication, this experience probably sounds familiar.
Your daily focus moves from managing what you eat to questioning whether you've eaten at all; however, your body still needs consistent nutrition to function properly. When taking GLP-1 medications and injections it’s important to eat by a schedule, not your appetite.
The Importance of Essential Nutrients in Your GLP-1 Journey
With diminished hunger cues, hitting your nutrition targets requires intentional planning. Here's the essential nutrients your body needs and practical ways to get them when you're not hungry.
Protein: Protein preserves muscle mass during rapid weight loss. Think of it as armor for your metabolism. At NJBC our team of registered dietitians recommend 60+ grams of protein daily. Here are some protein hacks for the appetite-challenged:
Morning Smoothie Power-Up:
1 scoop protein powder
½ cupGreek yogurt
Handful of spinach
½ banana + ¼ cup of berries
Savory Protein Bites:
2 hard-boiled eggs mashed
2 tbsp cottage cheese
Everything bagel seasoning
Serve on cucumber slices
Make 5 servings at once!
When a busy schedule prevents you from preparing a protein-rich meal, these convenient on-the-go options can help.
Grab-and-Go Protein:
Fairlife protein shakes
Adding protein powder in coffee
Greek yogurt
Nuts and seeds
Fiber: Constipation is a common side effect in GLP-1s, specifically when taking semaglutide (Ozempic®, Wegovy®). When digestion slows and appetite drops, fiber intake often falls short. To combat GLP-1 constipation, aim for a daily fiber intake of 35g.² To help you meet your daily fiber goal, incorporate fiber-rich foods such as fruits, vegetables, whole grains, nuts, and beans or lentils into your diet. If you find it difficult to meet your fiber needs through food alone, you can use fiber supplements like Benefiber.
Hydration: On GLP-1s it’s common to drink less water which can lead to dehydration.Dehydration can amplify side effects such as nausea, constipation, fatigue, and dizziness. Hydration is important to combat and essentially prevent these side effects. It’s also important for digestion, as it breaks down the food you eat.We recommend drinking 64oz of water daily.³
Micronutrients: When eating less overall, daily multivitamins can fill nutrition gaps and ensure you’re getting essential vitamins and minerals.
Scheduled Eating
Without hunger reminding you to eat, the clock becomes your best tool. Scheduled eating ensures consistent nutrition even when your appetite is silent, preventing unintentional meal skipping and the energy crashes that follow.
At New Jersey Bariatric Center®, our registered dietitians work with your schedule to create a realistic eating plan. Here's an example of a daily schedule:
Meal Prepping While Taking GLP1-s
When you’re not hungry, you may feel less motivated to cook. A solution to this is pre-made meals that you can grab without much effort. Dedicate a set day each week that works best for you for meal prepping. This proactive approach helps you stay consistent with your nutritional goals and establishes healthy eating as a regular, ingrained habit. Here’s an idea for a meal prep session:
Carbs - Cook quinoa/rice, portion out crackers, prep overnight oats
Veggies - Pre-portion nuts, cheese cubes, protein powder servings
Emergency Kit - Stock protein shakes and bars
Quick tip: Use clear containers to store your food so you can see your options.
Navigating Social Eating with No Appetite
Social dining can present unique challenges when you're on GLP-1 medication and managing reduced appetite. You might feel pressure to match the larger portions your friends or family are eating, even though you're simply not hungry. Restaurant menus can feel overwhelming when you need to find options that work with your smaller appetite, and portion sizes are far more than you can comfortably eat.
Strategies for Success When Dining: Consider ordering an appetizer as your main course, or requesting a to-go box when your meal arrives so you can portion out what feels right and save the rest. Another option is sharing an entrée with a companion. Focus on protein options that satisfy without requiring large portions, or choose a soup and salad combination that gives you variety without excess.
Prepare a Response for Social Eating: Having prepared responses ready can ease any social pressure around eating less. Simple, honest statements work well: you had a late lunch and want something light, your stomach has been sensitive so you're keeping it simple, or you're pacing yourself throughout the day.
There's no shame in using these strategies. They are practical tools that help you honor how your body feels while still enjoying time with others. The right approach is whatever allows you to eat comfortably and authentically in social settings without feeling pressured to consume more than you want.
Building Sustainable Habits
As you’re taking the medications, it’s important to build sustainable habits to keep track and support long-term weight loss. These habits can also help minimize common side effects like nausea, vomiting, and constipation that GLP-1s can often cause.
While tracking your progress, practice mindful eating and pay attention to your hunger and satiety signals. The food noise may not be as loud as it was, but the subtle hunger cues are still there.
Protein prioritization, scheduled eating, and portion awareness will help you stay on track for long-term success in your GLP-1 journey.
Never forget to celebrate the small wins. For example, if you hit your hydration goals, that’s a victory! This weight loss journey is different for everyone. Be patient with yourself as you navigate this new process.
For personalized support, our registered dietitians at New Jersey Bariatric Center® create customized nutrition plans that work with your GLP-1 medication. Call 908-481-1270 to schedule your consultation.
FAQs on GLP-1 Medications
Why do GLP-1 medications cause loss of appetite?
These medications work like your body's natural glucagon-like peptide-1 (GLP-1), a hormone released after eating that signals fullness and regulates blood sugar.¹ The medications amplify these natural signals by slowing digestion and reducing hunger signals in the brain, leading to a loss of appetite.¹
How soon does GLP-1 suppress appetite?
The timeline varies among individuals and depends on factors such as the dosage and your metabolism. Some may experience changes more quickly than others, however most people notice a gradual reduction in their appetite during the first week with more changes as time passes and taking weekly injections with consistency.⁴
What do I eat when I am not hungry on GLP-1s?
Focus on consuming small, nutrient-dense meals regularly throughout the day. These meals should include lean protein, healthy fats, and fiber. Prioritize foods such as lean chicken, fish, Greek yogurt, and nuts. This approach provides necessary nutrition without causing excessive fullness and can help mitigate muscle loss and potential side effects such as constipation and nausea.⁵ At New Jersey Bariatric Center®, our registered dietitians create customized meal plans, offer personalized nutrition guidance, and meal prep strategies to help you develop sustainable eating habits while taking weight loss medications.
Will I lose muscle on GLP-1s if I don't eat enough?
Yes, inadequate nutrition during rapid weight loss can lead to muscle loss alongside fat loss. This is why protein intake is important and we recommend 60+ grams of protein daily to help preserve muscle mass. When your body doesn't get enough protein and calories, it breaks down muscle tissue for energy, which can slow your metabolism and make long-term weight maintenance harder. Regular strength training combined with adequate protein intake helps protect muscle while taking GLP-1 medications. At New Jersey Bariatric Center®, our registered dietitians create personalized nutrition plans and our certified personal trainer works with patients to prioritize muscle preservation. If you're concerned about muscle loss, schedule a consultation to discuss your specific protein needs and eating strategy.
Why am I never hungry on Wegovy® / Zepbound®?
Wegovy® (semaglutide) and Zepbound® (tirzepatide) work by mimicking hormones that signal fullness to your brain and slow how quickly food leaves your stomach.¹ This dual effect eliminates the usual hunger signals you're accustomed to feeling. The medications are designed to create this appetite suppression. However, the absence of hunger doesn't mean your body doesn't need nutrition. Even without feeling hungry, you still need adequate protein, fiber, and hydration to support healthy weight loss and prevent muscle loss. This is why eating on a schedule becomes essential rather than waiting for hunger cues that may never come.
Sources
van Bloemendaal, L, J S ten Kulve, S E la Fleur, R G Ijzerman, and M Diamant. "Effects of glucagon-like peptide 1 on appetite and body weight: focus on the CNS". Journal of Endocrinology 221.1 (2014): T1-T16. < https://doi.org/10.1530/JOE-13-0414>. Web. 2 Dec. 2025.
Mehrtash F, Dushay J, Manson JE. I Am Taking a GLP-1 Weight-Loss Medication—What Should I Know? JAMA Intern Med. 2025;185(9):1180. doi:10.1001/jamainternmed.2025.1133
How to Combat Nausea on GLP-1 Medications (Ozempic®, Wegovy®, Zepbound®, Mounjaro®)
Nausea is a common side effect of GLP-1 weight loss medications like Ozempic®, Wegovy®, Zepbound® and Mounjaro®. It occurs due to delayed stomach emptying and the effect on appetite signals in the brain. Most nausea improves within 4-8 weeks as the body adjusts. Combat symptoms by starting with low doses, eating smaller meals, avoiding fatty foods, and staying hydrated. At New Jersey Bariatric Center, our medical weight loss team provides personalized support to help you manage side effects and stay on track with your treatment.
Managing nausea during those first weeks can help reduce symptoms and make treatment more tolerable. In this article, we will explore the connection between GLP-1s and nausea, strategies for prevention, ways to manage symptoms plus guidance on when to call your doctor.
Key Takeaways1:
40-70% of patients experience nausea when taking GLP-1 weight loss medications like Ozempic®, Wegovy®, and Mounjaro®.
Nausea on GLP-1s happens because the medication slows down how quickly your stomach empties, which makes you feel full faster.
How long nausea lasts depends on the medication and dose and is most pronounced when beginning the medication or increasing the dose.
Nausea decreases as your body adjusts to the changes from GLP-1s.
Why do GLP-1’s cause Nausea?
These medications mimic natural GLP-1, a naturally occurring hormone produced by the body that plays a crucial role in how our bodies regulate blood sugar and appetite. If people experience nausea while taking GLP-1 injections it may be due to:
Delayed Gastric Emptying: Similar to bariatric surgeries, GLP-1 medications slow down the rate at which food leaves the stomach. While this contributes to feelings of fullness which helps with weight loss, it can also leave patients with a lasting feeling of fullness, bloating, and nausea, especially if portions are too large or if meals are high in fat.
Direct Stimulation of GLP-1 Receptors in the Brain: GLP-1 receptors are found in various areas of the brain, particularly those involved in appetite control and the sensation of nausea. Activation of these receptors can directly trigger nausea.
Increased Satiety Signals: By enhancing the body's natural fullness or satiety signals, GLP-1 medications can contribute to feeling full more quickly and for a longer time following a meal. Even a small amount of overeating can leave a patient feeling uncomfortable and nauseous.2
How to Prevent and Minimize GLP-1 Nausea1
Taking proactive steps with your medication and diet can help you avoid nausea or reduce its severity:
Medication Management
Start Low, Go Slow: Most GLP-1 medications including Ozempic®, Wegovy®, Mounjaro® and Zepbound® are first prescribed at a low dose and gradually increased over several weeks or months. The slow start gives the body time to adjust to the medication and minimizes side effects. Increasing a dose too quickly or restarting the medication after an extended break can cause or increase nausea.
Timing of Dosing: Some individuals find that taking their GLP-1 medication at a specific time of day, such as in the evening, helps them sleep through some of the initial side effects. Others may choose a dose day that corresponds with a day off from work in order to allow time to adjust.
Dietary Strategies
Smaller, More Frequent Meals: Eating smaller portions throughout the day and stopping when full helps prevent overfilling the stomach. Be sure to talk with your dietitian about proper meal timing and frequency. Finding the right individualized balance is important as eating too often may work against the goal of weight loss and eating too little can contribute to nutrient deficiencies and eating too often may work against the goal of weight loss.
Avoid High-Fat and Greasy Foods: Fried foods, high fat meats and cheeses as well as processed snacks can increase feelings of heartburn and trigger nausea. Choose lean meats, low fat dairy and healthier plant-based fats from avocados, nuts, seed and olives. Bake, steam and air fry foods with minimal added fat to reduce both nausea and calories.
Choose Easy-to-Digest Foods: Lean proteins and minimally seasoned vegetables are the best foods to prioritize for healthy weight loss. Understandably, when dealing with nausea it is common to eat high carbohydrate foods, such as crackers, toast, rice, etc., before anything else. This is due to them being often bland, easily digestible, and they provide quick energy from the carbohydrates. These foods can help to reduce nausea temporarily but having too much can work against weight loss. Talk to your dietitian about how to balance carbohydrates in your diet.
Stay Hydrated: Drinking plenty of fluids throughout the day can help prevent dehydration, which can worsen nausea. Avoid sugary or acidic drinks and minimize caffeine. Many patients find electrolyte-containing beverages such as enhanced waters and zero calorie supplements significantly improve feelings of nausea.
Eat Slowly & Mindfully: Mindful eating, chewing food thoroughly, and taking time during meals can help improve digestion and minimize post-meal discomfort. Aim for 20-30 minutes per meal to allow enough time to feel full.
Managing Nausea
When nausea occurs despite your prevention efforts, many of these strategies can help manage symptoms:
Over-the-Counter Remedies:
Antacids: Medications like Tums or Rolaids can help neutralize stomach acid, which may improve nausea for some individuals.
Ginger: Ginger can be found in weight-loss friendly forms such as unsweetened ginger tea and sugar free ginger ale. It has a long history of use as an anti-nausea remedy and may help some with symptom relief.
Peppermint: Peppermint can help soothe the stomach. Unsweetened peppermint tea or sugar free mints may offer some relief.
In more severe cases, a doctor may prescribe medications to treat nausea.
Adjusting Medication Regimen: Your physician may consider reducing the dose of a GLP-1 medication, switching to another brand or temporarily pausing treatment if nausea is severe and persistent. We do not recommend adjusting medication dosages without first consulting your doctor.
Eat a Bland Diet: If nausea is severe or worsens, a temporary shift to a lower fiber, bland diet containing chicken breast, egg whites, white flaky fish, bananas, unsweetened applesauce and toast may help settle the stomach.
When to contact your doctor
While nausea is a common side effect weight loss medications, certain symptoms warrant immediate medical attention: If you experience severe nausea and vomiting, cannot keep fluids down, show signs of dehydration, experience abdominal pain or have any new or worsening symptoms, contact your doctor and seek medical attention immediately.
Communicating regularly with your doctor and dietitian is essential to best manage GLP-1-induced nausea and ensure the safe and effective use of these medications.3
Frequently Asked Questions
Which GLP-1 is least likely to cause nausea?
Both semaglutide (Ozempic® and Wegovy®) and tirzepatide (Mounjaro® and Zepbound®) may cause nausea though individual patient experiences vary. However, tirzepatide may lead to fewer or less severe nausea symptoms compared to semaglutide, according to studies conducted by independent researchers, such as Phase 3 randomized controlled trials (RCTs) found in PubMed's electronic databases.4
Does GLP-1 nausea ever go away?
Everyone is different and may not experience nausea or any side effects from both semaglutide (Ozempic® and Wegovy®) and tirzepatide (Mounjaro® and Zepbound®). However, in most cases the nausea is mild, manageable, and tends to subside over time.
How soon does nausea start after a GLP-1 injection?
Nausea after a GLP-1 injection can typically start within the first 24-48 hours after the first dose or shortly after an increased dose. It is often most noticeable during the first few weeks starting the medication, as your body adjusts.
Is it better to take GLP-1s at night or in the morning to prevent nausea?
While timing your GLP-1 medication may not prevent nausea, it can be a helpful management strategy. The ideal timing varies for each person.
Morning Dosing: Some patients prefer taking the medication in the morning. This allows them to actively manage any side effects, which may subside by bedtime. Nighttime Dosing: Others find that taking GLP-1s at night allows them to sleep through the nausea, effectively avoiding the discomfort.
Sources:
Gorgojo-Martínez JJ, Mezquita-Raya P, Carretero-Gómez J, et al. Clinical Recommendations to Manage Gastrointestinal Adverse Events in Patients Treated with Glp-1 Receptor Agonists: A Multidisciplinary Expert Consensus. Journal of Clinical Medicine. 2023;12(1):145. doi:https://doi.org/10.3390/jcm12010145
Zepbound (tirzepatide injection). Accessed December 5, 2025. https://zepbound.lilly.com/weight/how-to-use?gclsrc=aw.ds&utm_id=go_cmp-20643170522_adg-178869962134_ad-778107403406_kwd-2160125490606_dev-c_ext-_prd-_mca-_sig-Cj0KCQiA_8TJBhDNARIsAPX5qxSU-npJk9_87i4n169wrKeBUB-uLGG3NtBNMXn2Zf0k4Qs3BYehA1saAhiXEALw_wcB&utm_source=google&utm_medium=ppc&campaign=20643170522&adgroup=178869962134&ad=778107403406&utm_keyword=kwd-2160125490606&utm_term=go_cmp-20643170522_adg-178869962134_ad-778107403406_kwd-2160125490606_dev-c_ext-_prd-_mca-_sig-Cj0KCQiA_8TJBhDNARIsAPX5qxSU-npJk9_87i4n169wrKeBUB-uLGG3NtBNMXn2Zf0k4Qs3BYehA1saAhiXEALw_wcB&gad_source=1&gad_campaignid=20643170522&gbraid=0AAAAAqAD4ikqObKBh6zliiYc6cD-ubatH&gclid=Cj0KCQiA_8TJBhDNARIsAPX5qxSU-npJk9_87i4n169wrKeBUB-uLGG3NtBNMXn2Zf0k4Qs3BYehA1saAhiXEALw_wcB
Aronne LJ, Horn DB, le Roux CW, Ho W, Falcon BL, Gomez Valderas E, Das S, Lee CJ, Glass LC, Senyucel C, Dunn JP; SURMOUNT-5 Trial Investigators. Tirzepatide as Compared with Semaglutide for the Treatment of Obesity. N Engl J Med. 2025 Jul 3;393(1):26-36. doi: 10.1056/NEJMoa2416394. Epub 2025 May 11. PMID: 40353578.
Are Starbucks’ New Protein Coffees a Healthy Choice For Weight Loss?
By Karen Kelly, Registered Dietitian with over 20 years of specialized experience in weight management and bariatric nutrition at New Jersey Bariatric Center®
At New Jersey Bariatric Center®, we believe in providing our patients with the nutrition information they need to make informed choices. One question we've been hearing lately: "What about those new protein coffees at Starbucks? Are they a healthy choice to help me reach my weight loss goals?" While we recommend prioritizing protein to maintain muscle mass during weight loss, it’s important to look at the complete nutritional picture.
Are Starbucks’ Protein Coffees Healthy?
Starbucks’ protein coffees can support your weight loss goals when ordered strategically. For example, their Iced Vanilla Protein Latte offers 29 grams of protein, but contains 29 grams of sugar, amounting to 270 calories. Modifications like sugar-free syrups, non-fat milk, and skip high-calorie toppings can keep calories in check but homemade options offer better control over nutrition. Incorporating protein into your coffee can help boost satiety and metabolism. You can add a flavored protein powder to help avoid sugar and flavored creamers, as the powder can provide the desired sweetness.
Nutrition Facts
A single scoop of protein powder contains about 6g of protein, 25 calories, and 0g of sugar with 2 ingredients - whey protein and sunflower-derived lecithin to help it dissolve smoothly. Whey protein isolate is a dairy-based protein recognized for its comprehensive amino acid profile, with nine essential amino acids.¹ This means it provides all the essential amino acids your body needs to maintain muscle mass during weight loss.¹ When combined with protein-boosted milk in a grande latte that's up to 36g of protein in a single drink. Cold foam adds 15g of protein.
How Can Protein in Coffee Support Weight Loss?
Protein plays an important role in your surgical and medical weight loss journey. It preserves muscle mass during rapid weight loss after bariatric surgery and weight loss medications. It promotes satiety, keeping you full longer, which can reduce your overall calorie intake.² Protein also supports your metabolism, as it requires more energy for your body to digest.³
Adding protein to coffee can provide sustained energy without the excessive sugar that often comes with flavored coffee beverages. This can be another convenient way to hit your daily protein goals, especially with a reduced appetite while in the medical weight loss program or if you’ve had weight loss surgery.
Should You Choose Starbucks Protein Coffee for Weight Loss?
These drinks provide a substantial 27-36g of protein but still pack 200+ calories. Whether this fits your goals depends on how you’re structuring your daily nutrition. Starbucks offers sugar-free protein coffee options on its menu. Despite being promoted as sugar-free, a grande sized drink contains 9-16g of naturally occurring sugar from the milk, with no added sugars.
How To Build A Healthy Starbucks Protein Latte
It is still possible to enjoy your on-the-go latte from Starbucks by modifying the ingredients. Switching out whole milk for skim or almond milk and choosing sugar-free syrups are healthier options. For an extra boost of protein, cold foam is worth considering. Starbucks’ app allows you to customize your drink by providing a nutritional breakdown for all added ingredients.
For the most control of your calorie and nutrient intake, we recommend brewing your own healthy blend. Here’s a quick, weight loss friendly protein coffee I make at home that has a total of 175 calories with 30g of protein:
How to Make Protein Coffee At Home:
12 oz black coffee - zero calories
Grab your desired flavor of Premier Protein shake - whether it’s their winter mint chocolate for the season or good old fashioned vanilla.
Heat in microwave for 20 secs
Froth, add to coffee, and enjoy!
Starbucks vs Homemade:
Starbucks Grande Vanilla Protein Latte
Homemade Vanilla Protein Coffee
Calories: 310
Calories: 175
Fat: 6g
Fat: 3g
Carbohydrates: 36g
Carbohydrates: 4g
Sugar: 34g
Sugar: 1g
Protein: 27g
Protein: 30g
For more customized nutritional support, call us at 908-481-1270.
Protein Coffee FAQs
Does protein coffee taste like regular coffee?
Protein coffee’s texture is generally creamier and the flavoring depends on the type of protein powder or shake you use. If it is flavored with vanilla, caramel, chocolate, etc. the coffee will be rich and sweet. However, if the powder or shake has no flavoring, then it will be your usual coffee with milk taste. If you prefer flavored to give your coffee a nice taste, be sure it does not contain any artificial sweeteners or filler ingredients such as gums and other additives.
Can protein in coffee curb your appetite?
Given that protein promotes satiety - the feeling of fullness - adding it to your coffee can result in feeling full longer until your next meal. However, it is not a meal replacement. This is because it lacks essential nutrients found in whole protein foods, such as vitamins, minerals, fiber, and healthy fats. It’s important to have a balanced meal to get the full nutrients your body needs.
Is it okay to put protein powder in a hot drink?
Yes, you can put protein powder in a hot beverage, however it's best to mix it with cold or room temperature water ahead of time. This can prevent the powder from clumping and creating a paste. It's also best to let your hot beverage cool down a bit before adding it in.
'Tis the season for delicious, healthy holiday dishes. Check out our medical team's favorite holiday recipes below.
Dr. Goyal - Roasted Brussels Sprouts with Pancetta
Roasted brussels sprouts with pancetta is one of my favorite side dishes around the holidays. It’s full of fiber, antioxidants and vitamin K, plus even my kids will eat it!
Prep time: 10 min
Cooking time: 30 min
Ingredients:
1 lb. brussels sprouts, ends trimmed and quartered
1 clove garlic, minced
1 Tbsp. extra virgin olive oil or avocado oil
Salt and pepper to taste
4 oz. pancetta, diced
4 Tbsp. Balsamic Glaze
Instructions:
Preheat the oven to 400°F.
In a large bowl, toss together brussels sprouts, garlic, olive or avocado oil and salt and pepper. Place on a parchment lined baking sheet in a single layer.
Bake for 25-35 or until desired crispiness, tossing halfway through.
About 10 minutes before the timer goes off, place the pancetta in a small saute pan and cook for 5-7 minutes until crispy, set aside.
In a small saucepan over medium heat, gently warm the balsamic glaze.
Remove the brussels sprouts from the oven, add to a platter or tray, mix in cooked pancetta and drizzle with balsamic glaze. Serve warm.
Dr. Buwen - Family Brisket Recipe
My wife’s family celebrates Hanukkah and every year we make her grandmother’s brisket recipe which is always delicious. If you’re looking for a protein packed, star of the meal type of dish, try it out and let me know how you like it.
Prep Time: 10 min
Cook Time: 3 hours
Ingredients:
7-8 lb. lean cut brisket
1 tsp. Paprika
1 tsp. Garlic powder
Salt and pepper to taste
2 Tbsp. olive or avocado oil
4 Tbsp. sugar-free ketchup
1 packet Lipton Onion Soup Mix
1 cup water
1 chopped onion
5-6 chopped carrots
Instructions:
Pat brisket dry with a paper towel and season with paprika, garlic powder, salt and pepper.
Bring a large soup pot over high heat and add 2 tbsp. olive or avocado oil. Sear the brisket on both sides (about 5 minutes each).
Add 4 Tbsp. sugar free ketchup, onion soup mix, 1 cup water, chopped onions and carrots to the pot. Lower the heat to simmer. Cover to let steam/cook for 2 ½ hours, turning every 15 minutes.
Remove the brisket from the pot, let it stand for 15 minutes on a cutting board.
Slice the brisket against the grain and return to the pot for another hour. Serve!
Sweet potatoes are a classic holiday side but this version is made healthier with less sugar than the typical casserole but doesn’t sacrifice any flavor! You can enjoy this dish knowing it’s packed with heart healthy fiber and vitamin A.
Prep Time: 10 min
Cook Time: 35 min
Ingredients
3–4 sweet potatoes, cubed
2 tbsp olive oil
1 tsp cinnamon
½ tsp smoked paprika (optional)
½ tsp salt
⅓ cup chopped pecans
⅓ cup dried cranberries (reduced sugar preferred)
Instructions
Preheat the oven to 425°F and line a baking sheet with parchment paper.
Toss potatoes with oil, cinnamon, paprika, and salt.
Place in the oven for 30–35 minutes, stirring halfway.
Add cranberries and pecans in the last 5 minutes to lightly toast.
Are Wegovy® Pills and other Oral Weight Loss Medications Worth the Wait? What the Clinical Data Shows
Updated on December 23, 2025 to include the FDA approval of the Wegovy®pill by Novo Nordisk.
With FDA-approval of the Wegovy® pill by Novo Nordisk in December 2025, the first oral versions ofGLP-1 weight loss medications are scheduled to reach the market in January 2026. Eli Lilly’s weight loss pill, Orforglipron, is still awaiting FDA-approval and is expected by the summer of 2026.
This is good news for patients who prefer to avoid weight loss injections as these oral glp-1 weight loss pills combined with proper nutrition and physical activity offer a new way to treat obesity. For more than three years, injectable medications such as Wegovy® and Zepbound® have helped patients in New Jersey Bariatric Center®’s medical weight loss program, lose on average 15-20% of their excess body weight. Yet barriers remained for those with a strong aversion to needles or with limited access due to the cost of injectables until now but are these pills worth the wait?
Key Takeaways
Wegovy® Pill (oral semaglutide, 25 mg, Novo Nordisk) was FDA-approved for weight loss on December 22nd, 2025 with the medication expected to be available to patients in early January 2026.
Oral GLP-1 weight loss medication Orfoglipron (Eli Lilly) is nearing an FDA decision with available expect mid-2026
Clinical trials show meaningful results: 12-16%1,2 average weight loss, which is slightly less than injectables
Side effects are similar: mostly gastrointestinal, such as nausea or diarrhea, typically improving over 2–3 months.
Who could wait for approval and availability: patients with needle anxiety and stable health; those needing immediate metabolic improvement should consider current injectables, nutritional counseling or other weight loss options.
Oral GLP-1 Weight Loss Medications - The Clinical Evidence
Two companies—Novo Nordisk® and Eli Lilly®—are leading development of oral weight loss medications.
Oral Semaglutide® (Novo Nordisk)
Semaglutide is the active ingredient in popular weight loss injectable, Wegovy®. Lower-dose oral semaglutide (7–14 mg) is already approved under the brand name Rybelsus for type 2 diabetes. There is a new higher oral dose semaglutide that targets adults with obesity, regardless if they have type 2 diabetes. In May 2025, Novo Nordisk® submitted this new dose for FDA review. The application is based on a 64-week trial of 307 adults with obesity but without diabetes.3 Participants on oral semaglutide lost an average of about 16.6% of their body weight.4 The FDA approved the Wegovy® pill for weight loss on December 22, 2025 and it’s expected to be available to patients in early January 2026.3
Orforglipron (Eli Lilly)
Eli Lilly has been working on trials of a new oral weight loss medication called orfoglipron. In one study of 3,127 adults with obesity but not diabetes, those taking the highest dose lost an average of 27 pounds, or 12.4 % of body weight, over 72 weeks.1 Lilly expects to submit its FDA application of the new drug by the end of 2025.5
While injectable medications like Wegovy® and Zepbound® often achieve 15-20% weight loss6,7, the results of this trial are still clinically meaningful as a 10-15% reduction of body weight provides significant metabolic benefits.
Why Some Individuals May Prefer Pills vs Injectables
Needle Aversion: Anxiety around needles is more common than many realize. For some patients, it’s the main reason they decline or hesitate in deciding on injectable treatments. A daily pill removes that obstacle. The Wegovy® and other oral GLP-1 weight loss medication requires no refrigeration, no weekly preparation, and no logistical issues while traveling. For frequent travelers or those in shared living situations, that simplicity matters.
Tablets also have a potential manufacturing advantage: they’re easier to scale and distribute, which could improve supply and, over time, lower costs.
Weight Loss Medication Costs: Injectable GLP-1 medications range anywhere from $900 to $1500 per month out of pocket.In November 2025, Novo Nordisk and Eli Lilly both reached similar deals with the Trump administration to sell the lowest dose of oral GLP-1 medications for $149 per month out of pocket.9
Should You Wait for Oral Options?
The decision to wait to start your medical weight loss journey depends on your medical priorities and how comfortable you are with injections.
If you have obesity-related conditions—such as type 2 diabetes, hypertension, or sleep apnea—starting now with an approved injectable GLP-1 may make sense. Injectable GLP-1s such as Wegovy® have also demonstrated cardiovascular risk reduction in high-risk patients, an advantage not yet confirmed for the upcoming oral versions.8 If needle anxiety is the main obstacle and your health risks are stable, waiting for an oral alternative could be reasonable. The key is to use that time productively. For example, you could make an appointment to meet with a registered dietitian to lay out your nutrition goals and get started on a weight loss plan.
Oral GLP-1s share similar side effects with injectables—mainly nausea, diarrhea, constipation, and abdominal discomfort. In orforglipron trials, diarrhea appeared slightly more common than nausea. (1) Most gastrointestinal symptoms lessen after 8–12 weeks as the body adjusts.
What to Do While You Wait for Oral Weight Loss Meds
Establish care early. Connect with a weight-loss doctor at New Jersey Bariatric Center® so you’re ready when oral treatments launch or talk about other options you can begin now. Start seeing one of our registered dietitians now to help jumpstart your lifestyle changes and, ultimately, your weight loss.
Strengthen your foundation. GLP-1s improve weight loss results but depend on healthy habits. Start focusing on healthy nutritional habits and add more movement to your daily routine now.
Check your insurance. Coverage for weight loss medications vary. Understanding your benefits early can prevent delays later. Call your insurance provider to verify your coverage.
The Realistic Timeline
The FDA approved the Wegovy® pill on December 22, 2025 and the medication should be available to patients in early January 2026. If the FDA stays on this schedule, orforglipron is likely to receive approval in early-to-mid 2026. After FDA approval, production and insurance processes take time.
Next Steps
If you are struggling with weight-related health issues that are progressing now, meet with an NJBC weight loss doctor to discuss whether starting treatment now or waiting for oral medications is right for you.
Frequently Asked Questions
How much weight can I expect to lose with oral GLP-1 weight loss medications?
On average, patients can expect to lose 15-20% of their body weight when using oral GLP-1 weight loss medications.
How long will I need to take oral GLP-1 weight loss medications and will I regain the weight if I stop?
Similarly to GLP-1 injections, many patients will choose to continue treatment long-term for the best results. It is possible to regain weight after stopping any weight loss medication. At New Jersey Bariatric Center®, we offer a comprehensive approach that pairs weight loss medications with exercise and nutrition support to help you build sustainable habits that help to minimize weight re-gain.
Are oral GLP-1 weight loss pills going to be more affordable than GLP-1 injections?
Pricing information for oral GLP-1 weight loss medications has yet to be determined. This information will become available once the medication reaches FDA-approval and insurance companies offer coverage.
Sources:
Lilly’s oral GLP-1, Orforglipron, delivers weight loss of up to an average of 27.3 lbs in first of two pivotal phase 3 trials in adults with obesity | Eli Lilly and Company. (n.d.). https://investor.lilly.com/news-releases/news-release-details/lillys-oral-glp-1-orforglipron-delivers-weight-loss-average-273
Tirrell M. With FDA approval of Wegovy pill, new era of oral GLP-1 weight loss drugs begins. CNN. Published December 22, 2025. https://www.cnn.com/2025/12/22/health/wegovy-pill-glp1-weight-loss-drugs
Jastreboff, A. M., Aronne, L. J., Ahmad, N. N., Wharton, S., Connery, L., Alves, B., Kiyosue, A., Zhang, S., Liu, B., Bunck, M. C., & Stefanski, A. (2022). Tirzepatide once weekly for the treatment of obesity. New England Journal of Medicine, 387(3), 205-216. https://doi.org/10.1056/NEJMoa2206038
Wilding, J. P. H., Batterham, R. L., Calanna, S., Davies, M., Van Gaal, L. F., Lingvay, I., McGowan, B. M., Rosenstock, J., Tran, M. T. D., Wadden, T. A., Wharton, S., Yokote, K., Zeuthen, N., & Kushner, R. F. (2021). Once-weekly semaglutide in adults with overweight or obesity. New England Journal of Medicine, 384(11), 989-1002. https://doi.org/10.1056/NEJMoa2032183
Lincoff, A. M., Brown-Frandsen, K., Colhoun, H. M., Deanfield, J., Emerson, S. S., Esbjerg, S., Hardt-Lindberg, S., Hovingh, G. K., Kahn, S. E., Kushner, R. F., Lingvay, I., Oral, T. K., Michelsen, M. M., Plutzky, J., Tornøe, C. W., & Ryan, D. H. (2023). Semaglutide and cardiovascular outcomes in obesity without diabetes. New England Journal of Medicine, 389(24), 2221-2232. https://doi.org/10.1056/NEJMoa2307563
Jr BL. Trump strikes deal to lower cost of Wegovy, Zepbound weight loss drugs. NBC News. Published November 6, 2025. https://www.nbcnews.com/health/health-news/trump-weight-loss-drugs-cost-wegovy-zepbound-novo-nordisk-eli-lilly-rcna242309
This article is for educational purposes only and does not replace personalized medical advice. Consult an NJBC doctor to discuss which treatment approach is right for you.
